Dynamics of Micropollutant Adsorption to Polystyrene Surfaces Probed by Angle-Resolved Second Harmonic Scattering

Angle-resolved second harmonic scattering is used to probe the adsorption dynamics of aqueous cationic and anionic dye molecules onto polystyrene surfaces. The adsorptions of malachite green to negatively charged polystyrene and naphthol yellow S to positively charged polystyrene are both highly favorable, with Î"GAds values of -10.9 ± 0.2 and -10.27 ± 0.09 kcal/mol, respectively. A competitive displacement methodology was employed to obtain values for the adsorption free energies of various smaller neutral organic molecules, including the important micropollutant ascorbic acid, caffeine, and pentoxifylline. For charged adsorbers, electrostatic interactions appear to significantly contribute to adsorption behavior. However, electrostatic repulsion does not necessarily deter the adsorption of molecules with large uncharged moieties (e.g., surfactants). In these cases, the mechanism of adsorption is dominated by van der Waals interactions, with the surface charge playing a relatively minor role

Environmental impacts of alternative cement binders.

Cement production is among the most difficult industrial activities to decarbonize. Various measures have been proposed and explored to reduce its CO2 emissions. Among these measures, the substitution of portland cement (PC) clinker with alternative materials is arguably the most effective, and consequently is an area of high research and commercial interest. However, few studies have systematically quantified environmental impacts of alternative, i.e., non-PC, clinkers. Here, we quantify and compare environmental impacts arising from the production of binders derived from several of the most commonly investigated alternative cement systems. We show that binders derived from most of these alternative cements result in lower greenhouse gas (GHG) emissions as well as other indicators of environmental impacts relative to the PC binder. The extent of these reductions varies as a function of energy requirements for production, process-related emissions from clinker formation, and raw materials demand. While utilization of alternative cements can be environmentally beneficial, similar reductions in GHG emissions can be achieved through use of partial replacement of PC with mineral admixtures. In this work, we quantitatively demonstrate the potential for alternative binders to mitigate environmental burdens and highlight the need to consider trade-offs among environmental impact categories when assessing these products

The effect of aspect ratio on compressor performance

It is shown that the optimum aspect ratio at which max efficiency occurs is relatively low, typically between 1 and 1.5. At these aspect ratios, inaccuracies inherently exist in the decomposition of the flow field into freestream and endwall components due to the absence of a clear freestream. In this paper, a unique approach is taken; McKenzie’s ‘linear repeating stage’ concept is used plus a novel way of defining the freestream flow is proposed. Through this unique approach, physically accurate decomposition of the flow field for aspect ratios as low as ~0.7 can be achieved. This ability to accurately decompose the flow field leads to several key findings. Firstly, the endwall flow is found to be dependent on static pressure rise coefficient and endwall geometry, but independent of aspect ratio. Secondly, the commonly accepted relationship of endwall loss coefficient varying inversely with aspect ratio is physically inaccurate. Instead, a new term, which the authors refer to as ‘effective aspect rati o’, should replace aspect ratio. It is shown that not doing so can result in efficiency errors of ~0.6% at low aspect ratios. Finally, there exists a low aspect ratio limit below which the two endwall flows interact causing a large separation to occur along the span. From these findings, a low order model is developed to model the effect of varying aspect ratio on performance. The last section of the paper uses this low order model as well as a simple analytical model to show that to a first order, the optimum aspect ratio is just a function of the loss generated by the endwalls at zero clearance and the rate of change in profile loss due to blade thickness. This means that once the endwall configuration has been selected i.e. cantilever or shroud, the blade thickness sets the optimum aspect ratio.EPSR

Approach to Fungal Infections in Human Immunodeficiency Virus-Infected Individuals Pneumocystis and Beyond

Many fungi cause pulmonary disease in HIV-infected patients. Major pathogens include Pneumocystis jirovecii, Cryptococcus neoformans, Aspergillus species, Histoplasma capsulatum, Coccidioides species, Blastomyces dermatitidis, Paracoccidioides brasiliensis, Talaromyces marneffei, and Emmonsia species. Because symptoms are frequently non-specific, a high index of suspicion for fungal infection is required for diagnosis. Clinical manifestations of fungal infection in HIV-infected patients frequently depend on the degree of immunosuppression and the CD4 + TH cell count. Establishing definitive diagnosis is important because treatments differ. Primary and secondary prophylaxis depends on CD4+ TH cell counts as well as geographic location and local prevalence of disease

The impact of combustor turbulence on turbine loss mechanisms

Abstract A blade row which is located downstream of a combustor has an extremely high turbulence intensity at inlet, typically above 10%. The peak turbulent length scale is also high, at around 20% of the chord of the downstream blade row. In a combustor, the turbulence is created by impinging jets in cross flow. This may result in the turbulence being anisotropic in nature. The aim of this paper is to investigate the effect of combustor turbulence on the loss mechanisms which occur in a turbine blade row. The paper has a number of important findings. The combustor turbulence is characterized and is shown to be isotropic in nature. It shows that, when no pressure gradient is present, combustor turbulence increases the loss of a turbulent boundary layer by 22%. The mechanism responsible for this change is shown to be a deep penetration of the turbulence into the boundary layer. It shows that the presence of combustor turbulence increases the profile loss and endwall loss in the turbine cascade studied by 37% and 47%, respectively. The presence of combustor turbulence also introduces a freestream loss resulting in the total loss of the turbine cascade rising by 47%. When these loss mechanisms were applied to the vane alone, of an engine representative high pressure turbine, it was found to result in a 1.3% reduction in stage efficiency.Rolls-Royce and EPSRC Cenre for Doctoral Training in Gas Turbine Aerodynamic

The effect of non-equilibrium boundary layers on compressor performance

The paper investigates the effect of non-equilibrium behaviour of boundary layers on the profile loss of a compressor. The investigation is undertaken using both direct numerical simulation (DNS) of a mid-height section of a compressor blade and a reduced order model, MISES. The solutions are validated using experimental measurements made in the embedded stage of a multistage low speed compressor. The paper shows that up to 35% of the suction surface boundary layer of the compressor blade exhibits non-equilibrium behaviour. The size of this region reduces as the Reynolds number is increased. The non-equilibrium behaviour was found to reduce profile loss in most cases, however, in a range of cases where transition occurs through a small separation the presence of non-equilibrium behaviour was found to increase profile loss.</jats:p

On passion and moral behavior in achievement settings: The mediating role of pride

The Dualistic Model of Passion (Vallerand et al., 2003) distinguishes two types of passion: harmonious passion (HP) and obsessive passion (OP) that predict adaptive and less adaptive outcomes, respectively. In the present research, we were interested in understanding the role of passion in the adoption of moral behavior in achievement settings. It was predicted that the two facets of pride (authentic and hubristic; Tracy & Robins, 2007) would mediate the passion-moral behavior relationship. Specifically, because people who are passionate about a given activity are highly involved in it, it was postulated that they should typically do well and thus experience high levels of pride when engaged in the activity. However, it was also hypothesized that while both types of passion should be conducive to authentic pride, only OP should lead to hubristic pride. Finally, in line with past research on pride (Carver, Sinclair, & Johnson, 2010; Tracy et al., 2009), only hubristic pride was expected to negatively predict moral behavior, while authentic pride was expected to positively predict moral behavior. Results of two studies conducted with paintball players (N=163, Study 1) and athletes (N=296, Study 2) supported the proposed model. Future research directions are discussed in light of the Dualistic Model of Passion

Surface functionalisation of nanodiamonds for human neural stem cell adhesion and proliferation.

Biological systems interact with nanostructured materials on a sub-cellular level. These interactions may govern cell behaviour and the precise control of a nanomaterial's structure and surface chemistry allow for a high degree of tunability to be achieved. Cells are surrounded by an extra-cellular matrix with nano-topographical properties. Diamond based materials, and specifically nanostructured diamond has attracted much attention due to its extreme electrical and mechanical properties, chemical inertness and biocompatibility. Here the interaction of nanodiamond monolayers with human Neural Stem Cells (hNSCs) has been investigated. The effect of altering surface functionalisation of nanodiamonds on hNSC adhesion and proliferation has shown that confluent cellular attachment occurs on oxygen terminated nanodiamonds (O-NDs), but not on hydrogen terminated nanodiamonds (H-NDs). Analysis of H and O-NDs by Atomic Force Microscopy, contact angle measurements and protein adsorption suggests that differences in topography, wettability, surface charge and protein adsorption of these surfaces may underlie the difference in cellular adhesion of hNSCs reported here

Towards formal models of psychopathological traits that explain symptom trajectories

BACKGROUND: A dominant methodology in contemporary clinical neuroscience is the use of dimensional self-report questionnaires to measure features such as psychological traits (e.g., trait anxiety) and states (e.g., depressed mood). These dimensions are then mapped to biological measures and computational parameters. Researchers pursuing this approach tend to equate a symptom inventory score (plus noise) with some latent psychological trait. MAIN TEXT: We argue this approach implies weak, tacit, models of traits that provide fixed predictions of individual symptoms, and thus cannot account for symptom trajectories within individuals. This problem persists because (1) researchers are not familiarized with formal models that relate internal traits to within-subject symptom variation and (2) rely on an assumption that trait self-report inventories accurately indicate latent traits. To address these concerns, we offer a computational model of trait depression that demonstrates how parameters instantiating a given trait remain stable while manifest symptom expression varies predictably. We simulate patterns of mood variation from both the computational model and the standard self-report model and describe how to quantify the relative validity of each model using a Bayesian procedure. CONCLUSIONS: Ultimately, we would urge a tempering of a reliance on self-report inventories and recommend a shift towards developing mechanistic trait models that can explain within-subject symptom dynamics